The overall free energy changes during the transport of S. chinensislignans from the extracellular into the intracellular compartmenta.

aFree energy changes = −RTℓnKeq(J). R = 8.314 JK−1 mol−1. T = 310 K.bKeq′ is a pseudoequilibrium constant. K is the amount of outer membrane concentration defined in Table 5.cValue of ΔG3 was exampled by the largest value (of deoxyschisandrin) among these three lignans (be referred to Table 2).dThe value Keq in calculation of ΔG0,4 in reality is not an equilibrium constant because reversible reaction does not occur in the intracellular degradation process. The value was estimated by the difference between the initial and the final conditions (be referred to text).