Investigation of human peripheral T cells responsive to SARS-CoV-2 antigens. Investigation of human peripheral T cells responsive to SARS-CoV-2 antigens
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下载链接：
https://www.ncbi.nlm.nih.gov/bioproject/PRJNA766554
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资源简介：
To elucidate the T cell epitopes of SARS-CoV-2, we stimulated human PBMCs from healthy donors and convalescent COVID-19 patients with various SARS-CoV-2 antigens, sorted the activated T cells and performed sc-RNA and -TCR sequencing. We obtained thousands of T cell clonotypes that responded to SARS-CoV-2 antigens, and identified the epitopes and restricting HLAs of several clonotypes that were significantly expanded in the COVID-19 patients. Overall design: Determination of the TCR and mRNA expression of human T cells stimulated with SARS-CoV-2 antigens.
创建时间：
2021-09-27
