Crystal structure of p38alpha with an allosteric inhibitor 2
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Crystal structure of p38alpha with an allosteric inhibitor 2 Descriptor: Mitogen-activated protein kinase 14, ~{N}-(5,6-dimethoxy-1,3-benzothiazol-2-yl)-2-[(4-fluoranylphenoxy)methyl]-1,3-thiazole-4-carboxamide Authors: Hasegawa, S, Kinoshita, T. Deposit date: 2023-11-14 Release date: 2024-11-20 Last modified: 2025-03-05 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Distinct binding modes of a benzothiazole derivative confer structural bases for increasing ERK2 or p38 alpha MAPK selectivity. Biochem.Biophys.Res.Commun., 704, 2024
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2023-11-14
