Crystal structure of human MAO B in complex with (E)-3-(4-nitrophenyl)-1-(3-(trifluoromethyl)phenyl)prop-2-en-1-one (chalcone inhibitor, 4a)
收藏Protein Data Bank Japan2026-04-15 更新2026-04-19 收录
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Crystal structure of human MAO B in complex with (E)-3-(4-nitrophenyl)-1-(3-(trifluoromethyl)phenyl)prop-2-en-1-one (chalcone inhibitor, 4a) Descriptor: (2E)-3-(4-nitrophenyl)-1-[3-(trifluoromethyl)phenyl]prop-2-en-1-one, Amine oxidase [flavin-containing] B, FLAVIN-ADENINE DINUCLEOTIDE, ... Authors: Marchese, S, Binda, C. Deposit date: 2025-04-30 Release date: 2025-08-13 Last modified: 2026-04-15 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Design, synthesis, and biological evaluation of chalcone derivatives as selective Monoamine Oxidase-B inhibitors with potential neuroprotective effects. Eur.J.Med.Chem., 298, 2025
创建时间：
2025-04-30
