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Pigs lacking TMPRSS2 displayed fewer lung lesions and reduced inflammatory response when infected with Influenza A virus

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agdatacommons.nal.usda.gov2024-06-10 更新2025-03-22 收录
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https://agdatacommons.nal.usda.gov/articles/dataset/Pigs_lacking_TMPRSS2_displayed_fewer_lung_lesions_and_reduced_inflammatory_response_when_infected_with_Influenza_A_virus/24857601/1
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An experimental challenge of Influenza A virus in genetically modified TMPRSS2 knockout pigs. Resources in this dataset: Resource Title: Pigs lacking TMPRSS2 displayed fewer lung lesions and reduced inflammatory response when infected with Influenza A virus File Name: TMPRSS2 dataset.xlsx Resource Description: Supporting data for: Nasal shedding of A/swine/Iowa/A02524480/2020 (IA/20) H1N1 by virus titration on cell culture or qRT-PCR; Infection of IA/20 H1N1 in WT and TMPRSS2-/- pigs; Immunohistochemical (IHC) staining of Influenza A virus nucleoprotein; Cytokine and chemokine panel performed on bronchioalveolar lavage fluid.

一项针对基因改造敲除 TMPRSS2 的猪只感染流感 A 病毒的实验性挑战。本数据集包含以下资源: 资源标题:缺乏 TMPRSS2 的猪只感染流感 A 病毒时肺部病变减少,炎症反应降低 文件名:TMPRSS2 dataset.xlsx 资源描述:支持数据包括:A/swine/Iowa/A02524480/2020 (IA/20) H1N1 病毒的鼻拭子排出物通过病毒滴度在细胞培养或 qRT-PCR 中检测;WT 和 TMPRSS2-/- 猪只感染 IA/20 H1N1;流感 A 病毒核蛋白的免疫组化(IHC)染色;在支气管肺泡灌洗液中进行的细胞因子和趋化因子检测。
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