Figure S1 - Uncoupling between Inflammatory and Fibrotic Responses to Silica: Evidence from MyD88 Knockout Mice

IL-1R-KO mice treated with silica particles developed limited granuloma and macrophage and neutrophil infiltration but diffuse fibrosis. Neutrophil (A) and macrophage (B) numbers in the bronchoalveolar lavage (BAL) fluid of wild-type (WT) and IL1R-knockout (IL-1R-KO) mice treated with silica (SiO2, 2.5 mg/mouse) or saline solution (NaCl) and sacrificed at day 60. Bars represent means ± SEM (n = 4–6). These results were treated statistically by a t- test. ns indicates no statistically significant difference and ** = p (PDF)