Transcriptomic and Metabolomics dataset - Sauropus androgynus

Objectives Sauropus androgynus is a perennial shrub recognised for its ethnomedicinal applications and nutritional value. However, genomic and metabolomic information for this species remains limited. This study presents newly generated transcriptomic and metabolomic datasets derived from multiple tissue types, aimed at supporting functional annotation, gene discovery, and secondary metabolite research. Data Description Total RNA was isolated from leaf, flower, fruit, and stem tissues of S. androgynus, followed by high-throughput sequencing using the Illumina HiSeq platform. De novo assembly and functional annotation of the resulting reads produced a high-quality unigene dataset, with extensive coverage of key metabolic and regulatory pathways. Gene Ontology (GO) terms and KEGG pathway mapping revealed active participation in primary and secondary metabolism. In parallel, liquid chromatography-mass spectrometry (LC-MS) profiling was performed for each tissue, providing complementary chemical insights. These datasets offer a multi-layered molecular snapshot of S. androgynus, facilitating further investigation into its biosynthetic capabilities. All raw RNA-seq data are available in the NCBI SRA under BioProject accession PRJNA494978. The LC-MS spectra are exported and available in csv. Excel file format. Conclusion The integration of transcriptome and metabolite profiling offers a comprehensive molecular resource for S. androgynus. This dataset provides a foundation for exploring gene function, metabolic regulation, and the molecular basis of its medicinal properties.