Catalytic and Highly Enantioselective Friedel−Crafts Alkylation of Aromatic Ethers with Trifluoropyruvate under Solvent-Free Conditions
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https://figshare.com/articles/dataset/Catalytic_and_Highly_Enantioselective_Friedel_Crafts_Alkylation_of_Aromatic_Ethers_with_Trifluoropyruvate_under_Solvent_Free_Conditions/3040366
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资源简介：
Highly enantioselective Friedel−Crafts alkylation of simple and aromatic ethers (4a−l) with 3,3,3-trifluoropyruvate (3) was accomplished by
using chiral (4R,5S)-DiPh-BOX(1b)−Cu(OTf)2 complex (1 mol %) as a catalyst under solvent-free conditions. Excellent yields and enantioselectivities
(90−93% ee, after recrystallization up to 99% ee) of the Friedel−Crafts alkylation products were obtained.
创建时间：
2016-02-29
