ATAC-sequencing data for 923 enhancer deletion newborn mouse keratinocytes. ATAC-sequencing data for 923 enhancer deletion newborn mouse keratinocytes

We examined the ATAC-seq chromatin profiles of epidermis from newborn CRISPR-edited mice that have the 923 enhancer located within the Epidermial Differentiation Complex deleted. We examined two independent deletion lines, 923del and 923large, homozygous mutants, as well as wild type mice. We find overall there are not many differences in chromatin accessibility upon the loss of the 923 enhancer, though there are a few peaks of less accessible DNA within the EDC and more accessible DNA just outside the EDC. Overall design: Examination of accessible chromatin profiles by ATAC-seq in two 923 enhancer deletion lines and WT newborn mouse epidermis.