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This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
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创建时间：
2023-11-13
相关数据集
Depletion of H3K36me2 recapitulates epigenomic and phenotypic changes induced by the H3.3K36M oncohistone mutation
In this study, our results support a functional divergence between H3K36me2 and H3K36me3 and their non-redundant roles in H3K36M-driven oncogenesis Overall design: 17 ChIP-seq samples, 3 RNA-seq sampl
NIAID Data Ecosystem50
DNMT3A Reads and Connects Histone H3K36me2 to DNA methylation [RNA-seq]
DNA methylation at the 5-position of cytosine (5mC) is a crucial epigenetic mark in regulating biological processes including gene silencing, gene imprinting, and X chromosome inactivation. It has lon
NIAID Data Ecosystem00
Mitochondrial Fission 1 (FIS1) knockdown effect on the H3K27Ac status of leukemia cell line MOLM-13 cells. Mitochondrial Fission 1 (FIS1) knockdown effect on the H3K27Ac status of leukemia cell line MOLM-13 cells
To examine if loss of FIS1 would alter the H3K27Ac status of leukemic cells, we used shRNA to knock down the expression of FIS1 in leukemic cell line MOLM-13 cells and performed H3K27Ac CHIP-seq to ch
NIAID Data Ecosystem00
A prion accelerates proliferation at the expense of lifespan
Organisms often commit to one of two strategies: living fast and dying young or living slow and dying old. In fluctuating environments, however, switching between these two strategies could be advanta
Alliance of Genome Resources00
Addressing the specific roles of histone modifications in transcriptional repression [RNA-seq]
Our understanding of epigenetic processes is based on the hypothesis that individual posttranslational modifications of DNA and histones, or combinations thereof, function to direct unique downstream
NIAID Data Ecosystem00
