The tumorigenicity of LMW-E requires CDK2–associated kinase activity.
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Athymic mice were injected with 1×107 76NE6-TetR cells with inducible expression for empty vector, EL, LMW-E, ELR130A, and LMW-ER130A. Doxycycline was added to drinking water containing 1% sucrose 24 hours after injection and replaced twice weekly. The diameter of the tumors were measured and recorded weekly. Tumor incidence rate was estimated with exact 95% confidence intervals and Fisher's exact tests were used to compare tumor incidence rate between/among groups (*pR130A 500; LMW-E 500 vs. LMW-ER130A).
创建时间：
2015-12-02
