Alterations in Generalization Ability and Neuroimaging Markers with Respect to Aging and Alzheimer's Disease: A Comprehensive Meta-Analysis Dataset

Abstract: This dataset supports a comprehensive metadata analysis aimed at exploring emerging evidence for generalization deficits as a sensitive early measure of cognitive and neural decline in Alzheimer's disease (AD). It includes data on neuroimaging biomarkers, cognitive performance metrics related to generalization, and study-specific metadata extracted from multiple peer-reviewed publications. The data was curated and standardized to facilitate comparisons across studies, focusing on multimodal approaches to understanding aging and AD. This dataset serves as a resource for researchers investigating the interrelationships between generalization and neuroimaging, contributing to early AD diagnosis and interventions. It can be used for further meta-analyses, training predictive models, and hypothesis generation in aging and neuroimaging research.