Affinity-based chemoproteomic profiling of UNC0638 and UNC0737 in MCF7 and PBMC lysates identifies CHKA as a shared off-target.
收藏NIAID Data Ecosystem2026-05-02 收录
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https://www.omicsdi.org/dataset/pride/PXD056865
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资源简介：
To identify the molecular target(s) and elucidate the mechanism of action of UNC0638 and UNC0737, affinity-based chemoproteomics was performed. UNC0965, a biotinylated analogue of UNC0638, was immobilised on streptavidin-coated sepharose beads to enrich binding proteins from whole MCF7 or PBMC cell lysates. UNC0636 or UNC0737 were added as competitors in control experiments to identify specific binders.
创建时间：
2025-01-27
