Base editors, which are created through fusion of Cas9 nickase to either cytidine or adenine deaminase, efficiently catalyze site-specific nucleotide conversions with minimal indel rates1, 2. However,

NIAID Data Ecosystem50

Programmable RNA base editing with a single engineered protein

碱基编辑

基因治疗

Programmable base editing of RNA enables rewriting the genetic codes on specific sites. Current tools for specific RNA editing dependent on the assembly or recruitment of the guide RNA into an RNA/pro

NIAID Data Ecosystem40

Mus musculus strain:Fah-/- Raw sequence reads. Mus musculus strain:Fah-/-

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