Synthesis of Maremycins A and D<sub>1</sub> via Cycloaddition of a Nitrone with (<i>E</i>)-3-Ethylidene-1-methylindolin-2-one
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A concise synthesis of maremycins A and D1 has been accomplished via cycloaddition of a chiral cyclic nitrone with (E)-3-ethylidene-1-methylindolin-2-one as a key step. This synthesis clarifies the stereochemistry of the maremycins and is suitable for large-scale synthesis for biological screening.
创建时间:
2016-02-27



