Crystal structure of insulin receptor kinase domain in complex with an inhibitor Irfin-1
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Crystal structure of insulin receptor kinase domain in complex with an inhibitor Irfin-1 Descriptor: 5-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)-3H-pyrazolo[3,4-c]pyridazin-3-one, Insulin receptor Authors: Wu, J, Anastassiadis, T, Duong-Ly, K.C, Peterson, J.R. Deposit date: 2012-12-08 Release date: 2013-08-21 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.8 Å) Cite: A highly selective dual insulin receptor (IR)/insulin-like growth factor 1 receptor (IGF-1R) inhibitor derived from an extracellular signal-regulated kinase (ERK) inhibitor. J.Biol.Chem., 288, 2013
创建时间：
2012-12-08
