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Gene expression profiling of bone marrow and lung ILC2s

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NIAID Data Ecosystem2026-05-01 收录
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We found that CD45, a membrane bound tyrosine phosphatase important for T cell development, negatively regulated ILC2s in a cell-intrinsic manner. ILC2s in CD45-deficient mice exhibited enhanced proliferation and maturation in bone marrow and hyperactivated phenotypes in lung with alteration of cell metabolism. Examination two hundred of ILC2s freshly sorted from bone marrow and lung of CD45-deficient and control mice

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2023-10-28
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