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资源简介：
Human iPSC-derived hypothalamic neurons from super obese patients exhibit obesogenic transcriptional profiles and dysregulated hormone responses
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创建时间：
2018-04-21
相关数据集
Top 10 differentially expressed genes for the combined dataset of lean versus obese pigs as analyzed by DESeq2.
BaseMean: normalized mean read count for all animals; Log2FC: log2 fold change. FC: fold change; Padj: p-value adjusted for multiple testing (Benjamini and Hochberg as default by DESeq2). A positive f
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Single-cell RNA-sequencing of the mouse Dorsomedial Hypothalamic Nucleus (DMH)
Single-cell RNA-seq data from the mouse Dorsomedial Hypothalamic Nucleus (DMH) was generated following a modified protocol from https://www.nature.com/articles/s41586-020-2821-8. Briefly, six 7.5 week
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Obesity Alters the Composition and the Activity of the Hematopoietic Stem Cell Compartment Through Dysregulation of Gfi1 Expression (single-cell RNA-Seq). Mus musculus
Obesity is a chronic organismal stress that disrupts multiple systemic and tissue-specific functions. Here, we describe the effects of established obesity on the activity of the hematopoietic stem cel
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In situ promoter capture Hi-C data of differentiated SGBS human preadipocytes (days 0, 2, 8 and 16 of differentiation to adipocytes) and iPSC-derived hypothalamic neurons (days 12, 16 and 27 of differentiation). In situ promoter capture Hi-C data of differentiated SGBS human preadipocytes (days 0, 2, 8 and 16 of differentiation to adipocytes) and iPSC-derived hypothalamic neurons (days 12, 16 and 27 of differentiation)
Human SGBS preadipocytes were differentiated into adipocytes, and human iPSCs were differentiated into hypothalamic neurons. Cells were collected for in situ promoter capture Hi-C [PMID: 29988018] at
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