Identification of factors involved in somatic stem cells in the Drosophila testis. Identification of factors involved in somatic stem cells in the Drosophila testis

We report the transcriptional profiles obtained by next-generation sequencing (NGS) of FACS-purified somatic cyst stem cells (CySCs) from adult testes of Drosophila melanogaster. The goals of this study are to compare NGS-derived transcriptome profiling (RNA-seq) of wild type CySCs to those that have decreased Chinmo, increased Chinmo, elevated JAK/STAT signaling or elevated Hh signaling. Overall design: Examination of differentially-regulated genes in four types of CySCs, those with decreased Chinmo, increased Chinmo, increased JAK/STAT signaling or increased Hh signaling, compared to controls.