Proteome database of Klebsiella pneumoniae

Klebsiella pneumoniae is a
facultative anaerobic, lactose-fermenting, enterococci bacterium whose natural
habitat is the soil environment. Able to fix nitrogen, and thus a diazotroph,
the bacterium is also a natural commensal in the gastrointestinal tract of
humans. However, when displaced to the lungs, K. pneumoniae could cause
serious lung infections with characteristic sputum. This work sought to provide
the proteome information of K. pneumoniae by parsing the annotated
proteome file of the bacterium downloaded from UniProt. Comprising protein name
and amino acid sequence, the database was further refined by calculating
associated number of residues, molecular weight, and nucleotide sequence of
each protein in the proteome of the bacterium. Altogether, the resource should
be useful as starter kit for investigating the varied roles of K. pneumoniae
in the environment and in pathogenesis, which may help provide an overarching
theme for the metabolic processes and their regulation in this bacterium.