首页/数据集/Activated stroma dictates response to gemcitabine in combination with nab-paclitaxel in pancreatic ductal adenocarcinoma patient derived xenografts (PDAC-PDX).

Activated stroma dictates response to gemcitabine in combination with nab-paclitaxel in pancreatic ductal adenocarcinoma patient derived xenografts (PDAC-PDX).

NIAID Data Ecosystem2026-05-02 收录

胰腺癌化疗耐药

患者来源异种移植(PDX)

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE234259 数据链接链接失效反馈

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This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

应用场景：

创建时间：

2025-04-17

胰腺癌化疗耐药

microRNA生物标志物

FOLFIRINOX is superior to gemcitabine in patients with pancreatic cancer, but this regimen is associated with toxicity and biomarkers for response are warranted. MicroRNAs can mediate drug resistan

DataCite Commons2024-05-18 更新100

Transcriptome analysis of human pancreatic cancer cell lines and gemcitabine-resistant pancreatic cancer cell lines. Transcriptome analysis of human pancreatic cancer cell lines and gemcitabine-resistant pancreatic cancer cell lines

胰腺癌化疗耐药

转录组靶点筛选

Gemcitabine (GEM) alone and GEM-based chemotherapy are the preferred regimens for treating advanced unresectable and metastatic pancreatic cancer (PC). However, these treatments have limited efficacy

NIAID Data Ecosystem40

Table_1_TRIM37 Mediates Chemoresistance and Maintenance of Stemness in Pancreatic Cancer Cells via Ubiquitination of PTEN and Activation of the AKT–GSK-3β–β-Catenin Signaling Pathway.xls

胰腺癌化疗耐药

肿瘤干细胞维持

PurposeThe tripartite motif-containing family member TRIM37 is involved in a number of important biological and pathological processes, and it has recently been shown to be an essential regulator of p

NIAID Data Ecosystem20

Transcriptional changes in pancreatic cancer cells associated with gemcitabine resistance. Transcriptional changes in pancreatic cancer cells associated with gemcitabine resistance

胰腺癌化疗耐药

转录组分析

The goal of this study was to determine the transcriptional changes in pancreatic cancer cells after treatment with gemcitabine. Overall design: HPAFII cells were treated with PBS or Gemcitabine for 7

NIAID Data Ecosystem50

Regulation of chemosensitivity in pancreatic cancer cells. Regulation of chemosensitivity in pancreatic cancer cells

胰腺癌化疗耐药

药物耐受细胞衰老

We performed RNA-seq to investigate gene expression changes in pancreatic cancer cells following chemotherapeutic drug treatment. We identify a reversible senescence state among the drug-tolerant pers

NIAID Data Ecosystem30

Activated stroma dictates response to gemcitabine in combination with nab-paclitaxel in pancreatic ductal adenocarcinoma patient derived xenografts (PDAC-PDX).

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