Number of elite controllers (EC), their proportion, and demographic characteristics applying the CASCADE dataset to 10 definitions of EC found in the literature.

†Individuals in the cohort without adequate follow-up or number of HIV-RNA measurements to classify them as EC or non-EC.‡Based on number of seroconverters whose EC status could be determined.HIV risk groups: MSM: Men who have sex with men; IDU: Injection drug users; MSW: Heterosexual contact.Assuming all individuals with unknown EC status are non-EC.ŧA: HIV-positive ≥6 months, with ≥2 consecutive HIV-RNA B: HIV- positive ≥1 year, with ≥1 HIV-RNA C: HIV- positive ≥1 year, with ≥1 HIV-RNA D: HIV- positive ≥1 year, with ≥3 HIV-RNA E: HIV- positive ≥1 year, with ≥3 consecutive HIV-RNA F: HIV- positive ≥1 year, with ≥3 consecutive HIV-RNA G:HIV- positive ≥2 years, with ≥2 HIV-RNA H: HIV- positive ≥5 years, with ≥5 consecutive HIV-RNA I: HIV- positive ≥10 years, with all measured HIV-RNA J: HIV-positive ≥10 years, with ≥90% of HIV-RNA (≥2 HIV-RNA ever)