Crystal structure of the complex between MMP-8 and a non-zinc chelating inhibitor

Protein Data Bank Japan2023-11-01 更新2026-03-21 收录

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Crystal structure of the complex between MMP-8 and a non-zinc chelating inhibitor Descriptor: ACETOHYDROXAMIC ACID, CALCIUM ION, N-{[2-(2-amino-3,4-dioxocyclobut-1-en-1-yl)-1,2,3,4-tetrahydroisoquinolin-7-yl]methyl}-4-oxo-3,5,6,8-tetrahydro-4H-thiopyrano[4',3':4,5]thieno[2,3-d]pyrimidine-2-carboxamide 7,7-dioxide, ... Authors: Pochetti, G, Montanari, R, Mazza, F. Deposit date: 2008-07-08 Release date: 2009-03-03 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Extra Binding Region Induced by Non-Zinc Chelating Inhibitors into the S(1)' Subsite of Matrix Metalloproteinase 8 (MMP-8) J.Med.Chem., 52, 2009

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2008-07-08