Crystal structure of shorter construct of SHP2 unbound N-SH2 domain
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Crystal structure of shorter construct of SHP2 unbound N-SH2 domain Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, Isoform 1 of Tyrosine-protein phosphatase non-receptor type 11, ... Authors: Padua, R.A.P, Sullivan, C, Glaser, A, Ojoawo, A, Kern, D. Deposit date: 2025-09-05 Release date: 2026-01-07 Last modified: 2026-07-22 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Phosphatase SHP2 pathogenic mutations enhance activity by altering conformational sampling. Proc.Natl.Acad.Sci.USA, 123, 2026
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2025-09-05
