Effect of chromium nanoparticles and switching from a high-fat to a low-fat diet on the cecal microenvironment in obese rats

The cecal parameters in rats fed experimental diets. Cecal concentration and profile (% of total SCFAs) of short-chain fatty acids in rats. Cecal bile acid concentration of rats fed experimental diets. The activity of bacterial α-glucosidase and β-glucosidase, α -galactosidase and β –galactosidase, β -glucuronidase and β -xylosidase and their release rate in the cecum of rats. The in vivo experiment was performed using 84 outbred male Wistar rats fed a standard low-fat or high-fat/low-fiber (obesogenic) semi-purified rat diet without or with the dietary addition of two chromium (nanoparticles and picolinate; Cr-NP and Cr-Pic, respectively) forms.