Chemoenzymatic Total Syntheses of Ribisins A, B, and D, Polyoxygenated Benzofuran Derivatives Displaying NGF-Potentiating Properties
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https://figshare.com/articles/dataset/Chemoenzymatic_Total_Syntheses_of_Ribisins_A_B_and_D_Polyoxygenated_Benzofuran_Derivatives_Displaying_NGF_Potentiating_Properties/2309014
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资源简介：
Total syntheses of the structures, 1, 2, and 4, assigned to the biologically
active natural
products ribisins A, B, and D, respectively, have been achieved using
the microbially derived and enantiomerically pure cis-1,2-dihydrocatechol 5 as starting material. Key steps
include Suzuki–Miyaura cross-coupling, intramolecular Mitsunobu,
and tandem epoxidation/rearrangement reactions. As a result of these
studies, the structures of ribisins A and D have been confirmed while
that of congener B was shown to be represented by 31 rather
than 2.
创建时间：
2016-02-17
