Dietary fiber promotes antigen presentation on intestinal epithelial cells and development of small intestinal CD4+CD8αα+ intraepithelial T cells

To understand how changes in dietary fiber consumption and SFB colonization impact small intestinal epithelial cells (IECs) and consequently intraepithelial lymphocytes. Comparative gene expression analysis of RNA-seq data from intestinal epithelial cells of mice fed a standard chow diet (Control), a low fermentable fiber diet (NFF) or a standard chow diet and colonized with SFB (SFB).