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Human butyrylcholinesterase in complex with the R enantiomer of a chlorotacrine-tryptophan multi-target inhibitor.

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Protein Data Bank Japan2024-10-09 更新2026-03-21 收录
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https://pdbj.org/mine/summary/6i0c
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Human butyrylcholinesterase in complex with the R enantiomer of a chlorotacrine-tryptophan multi-target inhibitor. Descriptor: (2~{R})-2-azanyl-~{N}-[6-[(6-chloranyl-1,2,3,4-tetrahydroacridin-9-yl)amino]hexyl]-3-(1~{H}-indol-3-yl)propanamide, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Brazzolotto, X, Nachon, F. Deposit date: 2018-10-25 Release date: 2019-03-27 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (2.675 Å) Cite: Novel tacrine-tryptophan hybrids: Multi-target directed ligands as potential treatment for Alzheimer's disease. Eur.J.Med.Chem., 168, 2019
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2018-10-25
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