X-ray structure of human glutamate carboxypeptidase II (GCPII) in complex with a transition state analog of methotrexate-Glu

X-ray structure of human glutamate carboxypeptidase II (GCPII) in complex with a transition state analog of methotrexate-Glu Descriptor: (2S)-2-{[(R)-[(3R)-3-carboxy-3-{[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)amino}phenyl)carbonyl]amino}propyl](hydroxy)phosphoryl]methyl}pentanedioic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Barinka, C, Lubkowski, J. Deposit date: 2007-11-29 Release date: 2008-01-15 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Structural basis of interactions between human glutamate carboxypeptidase II and its substrate analogs J.Mol.Biol., 376, 2008