Crystal structure of the BRAF:MEK1 kinases in complex with AMPPNP
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Crystal structure of the BRAF:MEK1 kinases in complex with AMPPNP Descriptor: Dual specificity mitogen-activated protein kinase kinase 1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... Authors: Li, K, Gonzalez Del-Pino, G, Park, E, Eck, M.J. Deposit date: 2019-11-25 Release date: 2020-12-02 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.12 Å) Cite: Allosteric MEK inhibitors act on BRAF/MEK complexes to block MEK activation. Proc.Natl.Acad.Sci.USA, 118, 2021
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2019-11-25
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