Plasma concentrations of FTY720 and the phosphorylated form of FTY720, (S)-FTY720-P, after a single oral dose (0.3, 1.0, 3.0, 10.0 mg/kg) at 4, 8, 24, 48, and 72 hrs post-dose; values quantified by MS and are shown in nM (mean±SEM).
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Values in brain, muscle, and CSF at each timepoint in satellite rats in the 3 and 10 mg/kg dose groups are shown in the supplementary data.
创建时间:
2012-12-28



