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Knock in splice site mutations to establish the causality from the mutations to a transcript fusion

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NIAID Data Ecosystem2026-03-10 收录
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Knocked in mutations around the splice site of the second exon of CDKN1A in a cancer cell line A549 using CRISPR/Cas9. Observed the transcript fusion between CDKN1A and its downstream gene RAB44 as well as the activation of RAB44.

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2019-01-04
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