RNA editing provides prevalent adaptive and evolutionarily conserved proteomic diversities in Drosophila brains. Drosophila

RNA editing is the alternation of nucleic acid sequence on RNA level, which imposes modification on genome-encoded RNAs. In eukaryotic cells, the most dominant type of RNA editing is the substitution from adenosine to inosine (A-to_G), mediated by ADAR (adenosine deaminase acting on RNA). RNA editing is prevalent in brain tissues, it acts as an essential process to many organisms as it increases protein diversity without needing to change genomic sequences.