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The effects of SCAP deletion on gene expression of activated B cells

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE204913
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To investigate the role of SREBP signaling in B cell activation, we stimulated SCAP+/+CD19Cre/+ (WT) and SCAPfl/fl CD19Cre/+ (KO) B cells with LPS, anti-CD40 or anti-IgM for 24 hrs and performed RNA sequencing to identifiy the differences. We performed RNA seqencing comparing WT and KO B cell unstimulated (time 0) or stimualted with LPS, anti-CD40 or anti-IgM for 24 hrs
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2023-07-18
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