Processed Data for RegDiffusion-SCENIC pipeline
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https://zenodo.org/record/15096757
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资源简介：
Processed mice lung dataset from GSE276682 (Wu, 2025). This data includes a control group (n=3) and an intervention group (n=3). In the intervention group, mices were administered with intraperitoneal injection of 30mg/ml lipopolysaccharide (LPS) in saline to induce acute lung injury.
The raw FASTQ data was processed with cellranger to generate expression matrix. The count matrix was then processed following standard scanpy procedure and we focused on genes expressed in at least 5 cells. The input data has 55,129 cells and 3,701 genes.
It's used in the tutorial "Fast SCENIC GRN Analysis with RegDiffusion".
Wu, M., Wang, S., Chen, X., Shen, L., Ding, J., Jiang, H., 2025. Single-cell transcriptome analysis reveals cellular reprogramming and changes of immune cell subsets following tetramethylpyrazine treatment in LPS-induced acute lung injury. PeerJ 13, e18772. https://doi.org/10.7717/peerj.18772
创建时间：
2025-03-27
