CRYSTAL STRUCTURE OF DLK IN COMPLEX WITH COMPOUND 19

CRYSTAL STRUCTURE OF DLK IN COMPLEX WITH COMPOUND 19 Descriptor: (1S)-1-[4-[6-azanyl-5-(trifluoromethyloxy)pyridin-3-yl]-1-(3-morpholin-4-yl-1-bicyclo[1.1.1]pentanyl)imidazol-2-yl]-2-methyl-propan-1-ol, Mitogen-activated protein kinase kinase kinase 12 Authors: Zebisch, M, McEwan, P.A, Barker, J.J, Cross, J.B. Deposit date: 2023-04-24 Release date: 2023-07-26 Last modified: 2024-06-19 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Discovery of IACS-52825, a Potent and Selective DLK Inhibitor for Treatment of Chemotherapy-Induced Peripheral Neuropathy. J.Med.Chem., 66, 2023