Color scale indicates drug potency: darker blue = more potent, lighter blue = less potent. Anti-amoebic activity classified based on EC50 value as: Very high (0.001–0.999 μM), High (1.000–4.999 μM), M
IC50 values for treatment of iMACs and PMMs with benznidazole and posaconazole IC50 values were calculated based on the total number of mNeonGreen dots (mNG) and the number of parasites per 100 cells
Experiments were performed with coupled mitochondria with faf-BSA and GDP and in the absence of Ca2+. Essentially the same results were obtained in presence of Ca2+.
Raw data acquired with the spontaneous locomotor activity test. The column represents the number of movements measured from 3 to 6 min, that is the time equal to the observation period in FST. On the
