Structure of PPARG in complex with MTX-531

Structure of PPARG in complex with MTX-531 Descriptor: N-[(5P)-2-chloro-5-(4-{[(1R)-1-phenylethyl]amino}quinazolin-6-yl)pyridin-3-yl]methanesulfonamide, Peroxisome proliferator-activated receptor gamma, SULFATE ION, ... Authors: Whitehead, C.E, Leopold, J. Deposit date: 2023-04-05 Release date: 2024-06-12 Last modified: 2024-12-25 Method: X-RAY DIFFRACTION (1.855 Å) Cite: A first-in-class selective inhibitor of EGFR and PI3K offers a single-molecule approach to targeting adaptive resistance. Nat Cancer, 5, 2024