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Optogenetic response of mouse and macaque retinal ganglion cells

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Zenodo2020-08-01 更新2026-05-25 收录
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Data presented in "Towards optogenetic vision restoration with high resolution"<br> BioRxiv https://www.biorxiv.org/content/10.1101/470773v1, to appear in PLOS Computational Biology.<br> Please cite this paper if the data have been useful for you. Data contains multi-electrode array recordings of optogenetic response of retinal ganglion cells subject to checkerboard visual stimulation.<br> Mouse: blind rd1 mice (4-5 weeks old) with an AAV2 encoding ReaChR-mCitrine under a pan-neuronal hSyn promoter via intravitreal injections. <br> Macaque: retinal ganglion cells have been targeted with an AAV2 encoding a human codon optimized CatCh under a strong, RGC-specific promoter. Retinas were harvested three months after injection of the virus in the adult macaque retina.

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Zenodo
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2020-05-11
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