Effect of Bacillus subtilis on the intestinal flora of DSS-induced IBD model mice

The pathogenesis of inflammatory bowel disease (IBD) might be related to the local inflammatory damage and the dysbacteriosis of intestinal flora. Probiotics can regulate the intestinal flora and ameliorate IBD. The probiotic Bacillus subtilis strain B. subtilis JNFE0126 was used as the starter of fermented milk. However, the therapeutic effects of B. subtilis fermented milk on IBD remains to be explored. In this research, the therapeutic effect of the B. subtilis fermented milk on DSS-induced IBD model mice was evaluated.