DataSheet_1_Malignant Myoepithelioma of the Head and Neck: Demographics, Clinicopathological Characteristics, Treatment, and Prognosis.docx

Malignant myoepithelioma of the head and neck (HNMM) is a rare malignancy, and its characteristics and survival rates have not been well-defined. This study aimed to define the epidemiology of HNMM and identify the prognostic factors associated with the disease. Data on all patients diagnosed with HNMM between 1991 and 2016 were gathered from the Surveillance Epidemiology and End Results (SEER) database. The demographics, clinicopathological characteristics, treatment, and prognoses of the patients were described. Cox regression analysis was used to identify the prognostic factors, and the prognostic nomograms for overall survival (OS) and disease-specific survival (DSS) were constructed. A total of 333 cases of HNMM were identified. The average age at diagnosis was 60.6 years, and 50.1% of the patients were men. After diagnosis, 46.2% of patients underwent surgery alone, 43.5% of patients underwent surgery and radiotherapy, and 3.6% of patients received only radiotherapy. Survival analysis showed that the 5-year OS and DSS for all HNMM patients were 69.7 and 82.1%, respectively. In the multivariate analysis model, the undifferentiated pathological grade (P

头颈部恶性肌上皮瘤（HNMM）是一种罕见的恶性肿瘤，其临床特征及生存率尚未得到充分界定。本研究旨在阐明HNMM的流行病学特征，并识别与该疾病相关的预后因素。收集了1991年至2016年间SEER（Surveillance Epidemiology and End Results）数据库中所有被诊断为HNMM的患者的相关数据。描述了患者的流行病学特征、临床病理学特征、治疗手段及预后情况。利用Cox回归分析识别预后因素，并构建了总生存期（OS）和疾病特异性生存期（DSS）的预后图。共确定了333例HNMM病例。诊断时的平均年龄为60.6岁，其中50.1%的患者为男性。诊断后，46.2%的患者仅接受手术治疗，43.5%的患者接受了手术和放疗，而3.6%的患者仅接受了放疗。生存分析表明，所有HNMM患者的5年OS和DSS分别为69.7%和82.1%。在多因素分析模型中，未分化病理分级（P