Correlation analysis of pulmonary function tests (PFTs) with visual scores (VSs) and selected percentiles obtained from multidetector computed tomography (MDCT) attenuation histogram.

Summary of correlation analysis between pulmonary function tests (PFTs), visual scores (VSs), and selected percentiles (PERC) obtained from multidetector computed tomography (MDCT) attenuation histogram at initial MDCT and at 1-year follow-up. Pearson r coefficients were calculated for overall extent of abnormalities (OE), ground-glass opacities extent (GGO), reticulations extent (RET), honeycombing extent (HC) [all expressed as percentage of parenchyma involved (%)], and the density, expressed as Hounsfield Unit (HU), of selected percentiles obtained from the MDCT attenuation histogram with the percent predicted (%) of vital capacity (VC) and of diffusing capacity of the lung for carbon monoxide (DLCO) at baseline. The same coefficients were obtained for both longitudinal changes at 1-year (Δ) in VSs, expressed as percent per year (%/y), and in the density, expressed as Hounsfield Unit per year (HU/y), of selected percentiles obtained from the MDCT attenuation histogram with the variation, expressed as percent predicted per year (%/y), of VC% and of DLCO%. In bold p values statistically significant (pCorrelation analysis of pulmonary function tests (PFTs) with visual scores (VSs) and selected percentiles obtained from multidetector computed tomography (MDCT) attenuation histogram.