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Ribosome profiling experiments of LRRK2 mouse models

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G2019S mutaion of LRRK2 is known to increase mRNA translation. We perform ribosome profiling to study defective translation in mammalian LRRK2 models. We used G2019S LRRK2 transgenic mice, G2019S/D1994A LRRK2 transgenic mice, LRRK2 knockout mice. Mouse: 3 months old. Biological replicates were generated for mouse experiments.

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