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资源简介:
Improvement of base editing tools for editing scopes and off-target activities
应用场景:
创建时间:
2020-01-01
相关数据集
Additional file 9: of NmeCas9 is an intrinsically high-fidelity genome-editing platform
Table S7. Primer sequences used for on- and off-target deep sequencing analysis for all genomic editing sites analyzed by GUIDE-seq. (XLSX 28 kb)
Figshare2024-02-08 更新80
Gene replacement of alpha-globin with beta-globin restores hemoglobin balance in beta-thalassemia-derived hematopoietic stem and progenitor cells
Targeted deep sequencing of top-40 predicted off-target sites for HBA1-specific 3' UTR guide RNA reported in Cromer, et al., Nature Medicine, 2021.
NIAID Data Ecosystem50
Additional file 6 of What is the available evidence for the range of applications of genome-editing as a new tool for plant trait modification and the potential occurrence of associated off-target effects: a systematic map
Additional file 6. List of relevant studies and the systematic map database to answer secondary question 2.
Figshare2020-02-12 更新60
Metabolic effects of an aspartate aminotransferase-inhibitor on two T-cell lines
An emerging method to help elucidate the mode of action of experimental drugs is to use untargeted metabolomics of cell-systems. The interpretations of such screens are however complex and more exampl
NIAID Data Ecosystem30



