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Dithiane-Induced [3+2] Cycloaddition Tactic for the Convergent Synthesis of Dihydropyrrole and Pyrrole Derivatives

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Figshare2020-07-02 更新2026-04-28 收录
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An efficient transition-metal-free tactic for the convergent synthesis of substituted dihydropyrroles and pyrroles by β-chloro-vinyl dithiane cyclization with a broad range of imines was developed. [3+2] Cyclization and aromatization occur under these reaction conditions providing biologically relevant dihydropyrroles and pyrroles in good yields.

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2020-07-02
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