LAG-3 blockade reactivates the CD8+ T cell expansion program to re-expand contracted clones in the tumor
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The murine immune response to a pulmonary mycobacterial infection is slow to develop, allowing bacterial numbers to increase in the lung for several weeks after infection. We sought to enhance the pro
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Additional file 5 of Clonal tracing reveals diverse patterns of response to immune checkpoint blockade
Additional file 5: Table S4. LISA inference of transcription regulators that may best account for the differentially expressed genes.
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Paired VDJ and transcriptome single cell sequencing in LMP2 multimer-positive human T cells treated with anti-PD-L1 and anti-TIM3 antibodies.
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Blocking experiment CD83 and PD-1
Co-culture of dendritic cells and T cells with or without blocking antibodies against CD83 or PD-1.
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Synergistic Reversal of Intrahepatic HCV-Specific CD8 T Cell Exhaustion by Combined PD-1/CTLA-4 Blockade
Viral persistence is associated with hierarchical antiviral CD8 T cell exhaustion with increased programmed death-1 (PD-1) expression. In HCV persistence, HCV-specific CD8 T cells from the liver (the
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