Evaluation ABO-related clinical response to MSCs.

Patient characteristics and evaluation of clinical response to individual MSC-infusions in patients undergoing HSCT (Stockholm, n = 70; and Leiden, n = 35 MSC infusions). Blood type O (containing highest titers of both anti-A/B antibodies) was compared to blood type A, B, and AB (blood containing anti-B, anti-A, or no anti-A/B antibodies, respectively). Abbreviations: HSCT, hematopoietic stem cell transplantation; MSC, mesenchymal stromal cell; BG, blood group; HLA, human leukocyte antigen. Statistics: P-value is calculated using Mann-Whitney rank-sum test (for continuous variables), Fisher’s exact t-test (comparing two categorical variables), or Chi2-test (comparing more than two categorical variables).