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Antigen modifications improve mRNA-based influenza virus vaccines

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DataCite Commons2023-08-21 更新2025-04-16 收录
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Nucleoside-modified, lipid nanoparticle-encapsulated mRNAs have recently emerged as suitable vaccines for influenza viruses and other pathogens in part because the platform allows delivery of multiple antigens in a single immunization. mRNA vaccines allow for easy antigen modification, enabling rapid iterative design. Here, we studied protein modifications which could improve the safety and/or potency of mRNA-based influenza virus vaccines.

提供机构:
ImmPort
创建时间:
2023-08-21
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