Microglia, the resident immune cells of the brain, are crucial in the development of the nervous system. Recent evidence demonstrates that microglia modulate adult hippocampal neurogenesis by inhibiti
We analyzed the transcriptomes of adult primary rhesus macaque microglia that were exposed to 10 µg/mL uLPS, in the absence or presence of 5 µM P2RY6 antagonist MRS2578 Primary microglia cultured in m
IntroductionMatrix metalloproteinases MMP-2 and MMP-9 modulate inflammatory processes at the blood–brain barrier (BBB), but their presence and function in the dura mater remain unclear. We therefore i
Microglia are brain-resident, myeloid cells that play important roles in health and brain pathologies. While data on chromatin accessibility in activated murine microglia are available, there is no su
The skin integrates diverse signals discerned by sensory neurons and immune cells to elicit adaptive responses to a range of stresses. Considering interactions between nervous and immune systems, we q
