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Crystal structure of the extracellular region of the transmembrane serine protease hepsin with covalently bound preferred substrate.

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Protein Data Bank Japan2024-10-09 更新2026-03-21 收录
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Crystal structure of the extracellular region of the transmembrane serine protease hepsin with covalently bound preferred substrate. Descriptor: ACE-LYS-GLN-LEU-ARG-Chloromethylketone, Serine protease hepsin Authors: Herter, S, Piper, D.E, Aaron, W, Gabriele, T, Cutler, G, Cao, P, Bhatt, A.S, Choe, Y, Craik, C.S, Walker, N, Meininger, D, Hoey, T, Austin, R.J. Deposit date: 2005-03-30 Release date: 2005-05-03 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Hepatocyte growth factor is a preferred in vitro substrate for human hepsin, a membrane-anchored serine protease implicated in prostate and ovarian cancers Biochem.J., 390, 2005
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2005-03-30
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